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bioRxiv 预印本· Khan, D., Kwambana-Adams, B., Tientcheu, P. E., Thomas, S. A., Espinoza, J. L., John, G., Mamaghani, T., Ndow, P. S., Kinteh, M.-A., Worwui, A., Otchere, I. D., Mohammed, N. I., Nicol, M. P., Dupont, C. L., Antonio, M. ·· 1 天前AI 评分12

冈比亚农村5-14岁儿童上呼吸道菌群特征与肺炎链球菌定植相关

Upper respiratory tract bacterial microbiome features associated with Streptococcus pneumoniae colonisation, environmental and demographic factors among older children in a rural setting in The Gambia

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冈比亚134名5-14岁健康儿童8次随访的上呼吸道样本显示,肺炎链球菌定植与Moraxella、Streptococcus和Haemophilus丰度升高相关,未定植样本则富集Granulicatella和Filifactor,且定植样本Shannon多样性更低。年龄和季节是菌群组成的最强决定因素,年龄增长与Haemophilus、Moraxella等菌属丰度下降相关,革兰阳性菌主要在旱季富集。

来源:bioRxiv 预印本 · biorxiv.org