arXiv 定量生物学· Kartik Ayyer, Tej Varma Yenupuri, Johan Bielecki, Lutz A. Eichacker, J. Domingo Meza-Aguilar, Louise J. Persson, Lena Worbs, Patrick Adams, Roberto Alvarez, Adil Ansari, Alfredo Bellisario, Rebecca Boll, Carl Caleman, Sebastian Cardoch, Andrea Castoldi, Joe P. J. Chen, Cyril Danilevski, Merle Dechering, Simon Dold, Armando D. Estillore, Alberto De Fanis, Lukas V. Haas, Patrick Konold, David Lomitze, Abhishek Mall, Dimitra Manatou, I\~naki de Diego Martinez, Parichita Mazumder, Andrew J. Morgan, Anna Munke, Yevheniy Ovcharenko, Matteo Porro, Safi Rafie-Zinedine, Amit K. Samanta, Christina Schmidt, Arezu Sehati, Jonas A. Sellberg, Bj\"orn Senfftleben, Carolin Seuring, Zhou Shen, Nicusor Timneanu, Sergey Usenko, Daniel Westphal, August Wollter, Tamme Wollweber, Paul Lourdu Xavier, Henry N. Chapman, Janos Hajdu, Richard A. Kirian, Jochen K\"upper, Erik G. Marklund, Petra Fromme, Michael Meyer, Filipe R. N. C. Maia·· 2 小时前AI 评分20
欧洲 XFEL 实现真空下 1-MDa 膜蛋白复合物三维成像
Three-dimensional imaging of isolated membrane-protein complexes in vacuo with an X-ray laser
AI 导读
研究人员利用欧洲 XFEL，从 32 788 张单颗粒衍射图中三维重建了 1-MDa 膜蛋白复合物光系统 I（PS I）三聚体，分辨率达 3.8 nm。PS I 三聚体经电荷还原电喷雾电离气溶胶化后注入 XFEL 光束，部分氦气交换使背景散射降低 80%。重建出的盘状电子密度约 22 nm 宽、10 nm 厚，与去垢剂胶束中 PS I 三聚体尺寸相符。
来源：arXiv 定量生物学 · arxiv.org