Eric Topol· @EricTopol · X·· 2 小时前精选AI 评分60
AI 导读
Eric Topol 引用 AACR 旗下 Cancer Discovery 的研究指出，约4万名确诊癌症者接受 DNA 测序后，约15%携带致病性（致病）基因组变异（PVs）。他认为这一比例意味着相当一部分癌症本可通过预防或极早期发现来干预，而目前这类机会被完全错过。相关论文题为 Universal Germline Genetic Testing after a...，链接见 aacrjournals.org。
推荐理由
约4万名癌症患者中15%携带致病性胚系变异，这一比例提示现有检测路径可能遗漏了可预防或早期发现的窗口。
正文
About 15% of ~40,000 people who developed cancer have pathogenic (disease-causing) genome variants (PVs) when their DNA was sequenced.
That's a big proportion of cancer that would set up prevention or very early detection which is completely missed today @AACR @CD_AACR
https://aacrjournals.org/cancerdiscovery/article-abstract/doi/10.1158/2159-8290.CD-26-0971/788729/Universal-Germline-Genetic-Testing-after-a?redirectedFrom=fulltext
来源：Eric Topol · x.com