Cell· Jesse Zhang, Airol A. Ubas, Valentine Svensson, Nicole Thomas, Vishvak Subramanyam, Christopher Carpenter, Aidan Winters, Richard de Borja, Noam Teyssier, Neha Thakar, Umair Khan, Pooja V. Akella, Harper J. Green, John D. Thompson, Vuong Tran, Joseph Pangallo, Efthymia Papalexi, Ajay Sapre, Hoai Nguyen, Oliver Sanderson, Maria Nigos, Olivia Kaplan, Sarah Schroeder, Bryan Hariadi, Simone Marrujo, Crina Curca, Alec Salvino, Guillermo Gallareta Olivares, Ryan Koehler, Alexander Rosenberg, Charles Roco, Chiara Ricci-Tam, Matthew G. Jones, Alexander Dobin, Brian S. Plosky, Danielle E. Lyons, Daniele Merico, Nima Alidoust, Hani Goodarzi, Johnny Yu·· 14 天前AI 评分40
Tahoe-100M：单细胞分辨率绘制药物诱导分子表型图谱
Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution
AI 导读
Tahoe-100M 是一个包含 1 亿个单细胞转录组的数据图谱，记录了 50 种癌细胞系对约 1,100 种药物-剂量处理的响应。该资源在规模化层面将单细胞表型与分子表型配对，把药物机制与细胞响应关联起来，并作为开放获取的数据基础用于训练细胞行为预测模型。
来源：Cell · cell.com