Every breakthrough begins with patients willing to go first - determined to turn their own fight into hope for others. In BIO's new Patient Pioneers story, patients and families who have faced acute lymphoblastic leukemia, sickle cell disease, and multiple sclerosis reflect on what it means to be among the first to advance a new frontier in medicine - and to move the #FightOfOurLives forward. Their experiences differ, but they share one belief: progress is only possible when patients and scientists take big steps together.

Among them is Marci Pedrazzi McCue, the first person in a U.S. trial to receive CAR-T cell therapy for MS. As she puts it: "I think that when you're in a mindset of trying anything that's available to stop your disease, you're not afraid to be patient number one."

Their courage moves the fight forward - for every patient still waiting.

Watch their stories: https://fightofourlives.com/stories/patient-pioneers-stories/