Moderna· @moderna_tx · X·· 2026-08-19精选AI 评分80
AI 导读
Moderna与默沙东宣布，评估intismeran autogene联合KEYTRUDA（帕博利珠单抗）辅助治疗完全切除的IIB-IV期黑色素瘤的III期INTerpath-001试验取得阳性顶线结果。intismeran autogene是一款由默沙东与Moderna联合开发的在研mRNA个体化新抗原疗法，KEYTRUDA为默沙东的抗PD-1疗法。
推荐理由
Moderna与默沙东公布个体化新抗原疗法联合KEYTRUDA辅助治疗黑色素瘤的III期顶线结果，可了解该联合方案的关键进展。
正文
Moderna and @Merck today announced positive topline results from the Phase 3 INTerpath-001 trial evaluating adjuvant treatment with intismeran autogene, a novel investigational mRNA-based individualized neoantigen therapy jointly developed by Merck and Moderna, in combination with KEYTRUDA® (pembrolizumab), Merck's anti-PD-1 therapy, in patients with completely resected Stage IIB-IV melanoma.
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来源：Moderna · x.com