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bioRxiv 预印本· Hayashi, Y., Elias, R., Douglass, E., Yamamoto, A., Schuler, M., Feng, M., Batourina, E. Y., Geller, A. E., Choi, W., Colocho, G., Arbuiso, A., Jin, S., Aragaki, A. K., Ruland, C., Rapiey, S., Hoffman-Censits, J., Kates, M., Patel, S., Singla, N., Smith, A., Russell, S., Li, H., Warrick, J. I., Baraban, E., Allenspach, K., Mendelsohn, C. L., Matoso, A., Hahn, N. M., McConkey, D. J., Johnson, B. A. ·· 10 小时前AI 评分22

上皮-间质转化与M2巨噬细胞驱动小鼠及人肉瘤样尿路上皮癌侵袭性

Epithelial to mesenchymal transition and M2 macrophages drive aggressiveness in murine and human sarcomatoid urothelial carcinoma.

AI 导读

研究团队通过BBN诱导小鼠膀胱癌并在缺乏成熟B/T细胞的小鼠中传代,建立了BBN966(肉瘤样)、BBN964(肉瘤样与鳞状混合)和BBN975(鳞状)三株变异亚型膀胱癌细胞系。

来源:bioRxiv 预印本 · biorxiv.org