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Moderna· @moderna_tx · X·· 2026-06-01精选AI 评分72
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Moderna公布2b期随机KEYNOTE-942/mRNA-4157-P201研究的五年随访详细结果,该研究评估个体化mRNA新抗原疗法intismeran autogene(mRNA-4157或V940)联合默沙东抗PD-1疗法KEYTRUDA(帕博利珠单抗)用于完全切除后的高危黑色素瘤(III/IV期)患者。

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Moderna公布mRNA-4157联合帕博利珠单抗治疗高危黑色素瘤的五年随访数据,读者可据此了解个体化新抗原疗法的长期疗效走向。

正文

Today we announced detailed results from a planned five-year follow-up analysis of the Phase 2b randomized KEYNOTE-942/mRNA-4157-P201 study evaluating intismeran autogene (mRNA-4157 or V940), an investigational mRNA-based individualized neoantigen therapy, in combination with KEYTRUDA® (pembrolizumab), @Merck's anti-PD-1 therapy, in patients with high-risk melanoma (stage III/IV) following complete resection.

These data will be presented today at the 2026 American Society of Clinical Oncology (@ASCO) Annual Meeting (May 29-June 2) and published simultaneously in ASCO’s Journal of Clinical Oncology.

Read more: https://feeds.issuerdirect.com/news-release.html?newsid=8957702549517575&symbol=MRNA

来源:Moderna · x.com