bioRxiv 预印本· Hurabielle, C., Wang, Y. V., Castillo-Rojas, B., Wang, C.-Y., Caspar, C., Asaki, J., Dayao, M., Calcoen, M., Merrill, E. D., Bodansky, A., Klepper, A., Chung, E. N., Vissers, C., Zorn, K. C., Anderson, M. S., Wilson, M., Izmirly, P., Buyon, J., Yazdany, J., Dall'Era, M., Ye, C. J., DeRisi, J. L. ·· 2 天前AI 评分30
SLE线性表位图谱揭示与疾病及疾病活动度相关的新抗原，YTHDF2与EBV BZLF1交叉反应
Longitudinal linear-epitope profiling of SLE identifies novel antigens associated with disease and disease activity
AI 导读
研究团队用PhIP-seq对695例SLE患者和301例健康对照的1,268份血浆样本做线性表位无偏分析，机器学习识别出可区分SLE与健康对照的共享自身反应性特征，并显著富集RNA结合蛋白靶点。
来源：bioRxiv 预印本 · biorxiv.org