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Moderna· @moderna_tx · X·· 2026-08-20精选AI 评分80
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Moderna与默沙东公布III期INTerpath-001研究阳性结果,评估个体化新抗原疗法intismeran autogene联合帕博利珠单抗用于完全切除的IIB-IV期黑色素瘤辅助治疗。

推荐理由

原文给出III期INTerpath-001研究在黑色素瘤辅助治疗中的阳性结果,读者可据此了解个体化新抗原疗法联合PD-1的进展。

正文

Along with our partners at @Merck, we announced positive results from the Phase 3 INTerpath-001 study of intismeran autogene, our investigational individualized neoantigen therapy, in combination with pembrolizumab as adjuvant treatment in patients with completely resected Stage IIB-IV melanoma. This marks the first and only combination regimen to demonstrate a clinically meaningful improvement over pembrolizumab alone, a current standard-of-care for these patients.

In our latest IR Insights, members of our executive team sat down to reflect on what this means: https://www.modernatx.com/ir-insights-phase-3-intesmeran

来源:Moderna · x.com